D31 Hemodynamic-guided therapy in essential hypertension (EH)

Hemodynamic Patterns in Essential Hypertension.

Systemic Hemodynamic Effects of Bethanidine in Essential Hypertension By STEVEN

Although available elsewhere, bethanidine remains under study in the U.S. and its hemodynamic effects are unreported. Therefore, 29 patients with moderately severe essential hypertension received one of four oral dose levels (0.10, 0.25, 0.35, or 0.50 mg/kg) of the postganglionic sympatholytic drug. Blood pressure was reduced only in the 14 patients receiving the highest dose. This was demonstr...

Systemic hemodynamic effects of bethanidine in essential hypertension.

Although available elsewhere, bethanidine remains under study in the U.S. and its hemodynamic effects are unreported. Therefore, 29 patients with moderately severe essential hypertension received one of four oral dose levels (0.10, 0.25, 0.35, or 0.50 mg/kg) of the postganglionic sympatholytic drug. Blood pressure was reduced only in the 14 patients receiving the highest dose. This was demonstr...

The importance of hemodynamic considerations jn essential hypertension

Hypertension is a major risk factor for cardiovascular morbidity and mortality. Antihypertensive therapy consistently reduces complications from stroke and congestive heart failure, whereas beneiits from the treatment of ischemic heart disease events are variable. Several plausible explanations, including hemodynamic hypotheses, have been put forth to account for the failure of treatment to mor...

Hemodynamic changes in hypertension.

DESPITE a vast amount of work devoted to the subject the nature of the fundamental hemodynamic changes in chronic, human hypertension is poorly understood. In this necessarily brief discussion the main outlines of the problem will be sketched in emphasizing the respective roles of the heart, large arteries and resistance vessels. Other factors such as the sympathetic nervous system, the barorec...